SAFe: Market Share Increase. Rapid Growth. What is the recipe?

Some time ago, there was a webinar recorded by VersionOne: How to use SAFe® to Deliver Value at Enterprise Scale Q&A Discussion with Dean Leffingwell).   If you fast-forward to about 23 min, 20 seconds into the recording, you will hear the following statement: “…We don’t typically mess with your organizational structure because that is a pretty big deal…”

This statement somewhere puzzled me.  While graphic representation of SAFe framework is nowhere short of supporting organizational complexity, I was still under impression that organizational design improvements/simplification are included in SAFe teaching.  To me, an ability to influence first-degree system variables, such as Organizational Structure, is critical.  Without this ability, any attempt to improve organizational agility and system dynamics would be short-term and limited.  Even such important second-degree system variables, as organizational culture, values, norms, behaviors, policies, agile engineering practices usually bring limited results if organizational structure remains unchanged.